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INSTITUTE OF PHARMACY




                                  COURSE MODULE


Course Name: Pharmacology-III                               Course Code: PHM 4.7.4
Class: B.Pharm (Sem. 7)                       Total Lectures: 40 Practicals: 4hr/week
                                                                   Theory: 3hr/week
Lecturer (Ms. Japinder Kaur; M.pharm, Pharmacology)                Tests: 2
E-mail: gilljapinder@gmail.com                                     Assignments: 2


Course Description
This is a core pharmacology subject. This course is designed to provide the detailed study
of drugs (pharmacokinetics & pharmacodynamics) acting on G.I.T, Endocrine system,
chemotherapy & to explain principles of toxiocology.


Course Topics
   •   Drugs Acting on the Gastrointestinal Tract
   •   Pharmacology of Endocrine system
   •   Chemotherapy
   •   Principles of Toxicology
Teaching Methods:

        Lectures, Assignments, Presentations, Group discussions and tests

Learning Outcomes:

   1. Certain drugs specific for the treatment of specific diseases (therapeutic effect).
   2. Unwanted reactions of the drugs (side-effects or toxicity).
   3. Practical applications of pharmacology in our daily life and its scope in field of
      Pharmacy
Module Outline:

   S.No.                               Topics to be covered
     1.    Drugs acting on the gastrointestinal tract: Antacids
     2     Anti-secretory and Anti-ulcer drugs
     3.    Laxatives and Antidiarrhoeal drugs
     4.    Appetite stimulants and suppressants
     5.    Emetics and anti-emetics.
     6.    Carminatives and Demulcents
     7.    Protectives and Adsorbants
     8.    Astringents and digestants enzymes and mucolytics
     9.    Pharmacology of Endocrine system: hypothalamic and pituitary hormones
    10.    Thyroid hormones and anti thyroid drugs
    11.    Parathormone, calcitonin and vitamine D.
    12.    Insulin.
    13.    Glucagon
    14.    Oral hypoglycaemic agents
    15.    -do-
    16.    ACTH and Corticosteroids
    17.    Androgens and Anabolic Steroids
    18.    Estrogens, Progesterone and Oral contraceptives
    19.    -do-
    20.     Drugs acting on uterus.
    21.    General principles of Chemotherapy
    22.    Sulfonamides and cotrimoxazole
    23.    Antibiotics: Penicillins and cephalosporins
    24.    -do
    25.    Erythromycin, quinolones and miscellaneous antibiotics.
    26.    -do-
    27.    Chemotherapy of tuberculosis and leprosy
    28.    -do-
    29.    Chemotherapy of Fungal diseases
    30.    Chemotherapy of viral diseases
    31.    Urinary tract infections
    32.    sexually transmitted diseases
    33.    Chemotherapy of malignancy
    34.    -do-
    35.    Immunosuppressive agents
   36.     Principles of toxicology: Definition of poision,General principles of
           treatment of poisioning
   37.     -do-
38.   Treartment of Barbiturates, opioids, organophosphorous and atropine
      poisioning
39.   -do-
40.   Heavy metals and heavy metal antagonists
Assignment topics
Antacids
Anti-secretory
Anti-ulcer drugs
Laxatives and Antidiarrhoeal drugs
Appetite stimulants and suppressants
Emetics and anti-emetics.
Carminatives and Demulcents
Protectives and Adsorbants
Astringents and digestants enzymes and mucolytics
Pharmacology of Endocrine system: hypothalamic and pituitary hormones
Thyroid hormones and anti thyroid drugs
Parathormone, calcitonin and vitamine D.
Insulin.
Glucagon
Oral hypoglycaemic agents
ACTH and Corticosteroids
Androgens and Anabolic Steroids
Estrogens and Oral contraceptives
Progesterone
Drugs acting on uterus.
General principles of Chemotherapy
Sulfonamides and cotrimoxazole
Antibiotics: Penicillins
Cephalosporins
Erythromycin
Quinolones
Miscellaneous antibiotics.
Chemotherapy of tuberculosis
Leprosy
Chemotherapy of Fungal diseases
Chemotherapy of viral diseases
Urinary tract infections
sexually transmitted diseases
Chemotherapy of malignancy
Immunosuppressive agents
Principles of toxicology
Definition of poision,General principles of treatment of poisioning
Treartment of Barbiturates, opioids,
Organophosphorous and atropine poisioning
Heavy metals and heavy metal antagonists
                                                 Score
      Modes of Assessment
Assignment/Attendance                             10
 Presentation/Tests                               10
 Mid semester exam-I                              40
 Mid semester exam-II                             40
Modes of Assessment:




Instruction for students:

1.    Assignment marks will be awarded only after conducting viva-voce which will be
      on the day of assignment submission.
2.    Late submission is not permissible and will attract minimum awards.
3.    For presentation, whole of the class is divided in to 5 groups and each group is
      again subdivided into 3 subgroups. Each subgroup has 4 students.
4.     Each group is assigned different subject for the presentation day.
5.    The presentation day attendance is equivalent to 4 lectures.
6.    The synopsis must be submitted one week before the presentation.
7.    75% attendance is mandatory, below this percentage; student will not be allowed
      to appear in the examination.
8.    The students will record the details of practicals in the practical note book and
      get it checked every time from the instructor after the experiment has been
      completed




Text books:

1.    Tripathi, Experimental Pharmacology, Edition 5.
2.    Kulkarni, S.K., A Handbook of Experimental Pharmacology.

References:

1.    Goodman and Gilman’s, The Pharmacological Basis of Therapeutics. Editor J.G.
      Hardman et al. Pergamon Press.
2.    Rang, M.P., Dale M.M. and Riter, J.M. Pharmacology. Churchill Livi.

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Pharmacology-III: Drugs Acting on Gastrointestinal, Endocrine Systems

  • 1. INSTITUTE OF PHARMACY COURSE MODULE Course Name: Pharmacology-III Course Code: PHM 4.7.4 Class: B.Pharm (Sem. 7) Total Lectures: 40 Practicals: 4hr/week Theory: 3hr/week Lecturer (Ms. Japinder Kaur; M.pharm, Pharmacology) Tests: 2 E-mail: gilljapinder@gmail.com Assignments: 2 Course Description This is a core pharmacology subject. This course is designed to provide the detailed study of drugs (pharmacokinetics & pharmacodynamics) acting on G.I.T, Endocrine system, chemotherapy & to explain principles of toxiocology. Course Topics • Drugs Acting on the Gastrointestinal Tract • Pharmacology of Endocrine system • Chemotherapy • Principles of Toxicology Teaching Methods: Lectures, Assignments, Presentations, Group discussions and tests Learning Outcomes: 1. Certain drugs specific for the treatment of specific diseases (therapeutic effect). 2. Unwanted reactions of the drugs (side-effects or toxicity). 3. Practical applications of pharmacology in our daily life and its scope in field of Pharmacy
  • 2. Module Outline: S.No. Topics to be covered 1. Drugs acting on the gastrointestinal tract: Antacids 2 Anti-secretory and Anti-ulcer drugs 3. Laxatives and Antidiarrhoeal drugs 4. Appetite stimulants and suppressants 5. Emetics and anti-emetics. 6. Carminatives and Demulcents 7. Protectives and Adsorbants 8. Astringents and digestants enzymes and mucolytics 9. Pharmacology of Endocrine system: hypothalamic and pituitary hormones 10. Thyroid hormones and anti thyroid drugs 11. Parathormone, calcitonin and vitamine D. 12. Insulin. 13. Glucagon 14. Oral hypoglycaemic agents 15. -do- 16. ACTH and Corticosteroids 17. Androgens and Anabolic Steroids 18. Estrogens, Progesterone and Oral contraceptives 19. -do- 20. Drugs acting on uterus. 21. General principles of Chemotherapy 22. Sulfonamides and cotrimoxazole 23. Antibiotics: Penicillins and cephalosporins 24. -do 25. Erythromycin, quinolones and miscellaneous antibiotics. 26. -do- 27. Chemotherapy of tuberculosis and leprosy 28. -do- 29. Chemotherapy of Fungal diseases 30. Chemotherapy of viral diseases 31. Urinary tract infections 32. sexually transmitted diseases 33. Chemotherapy of malignancy 34. -do- 35. Immunosuppressive agents 36. Principles of toxicology: Definition of poision,General principles of treatment of poisioning 37. -do-
  • 3. 38. Treartment of Barbiturates, opioids, organophosphorous and atropine poisioning 39. -do- 40. Heavy metals and heavy metal antagonists
  • 4. Assignment topics Antacids Anti-secretory Anti-ulcer drugs Laxatives and Antidiarrhoeal drugs Appetite stimulants and suppressants Emetics and anti-emetics. Carminatives and Demulcents Protectives and Adsorbants Astringents and digestants enzymes and mucolytics Pharmacology of Endocrine system: hypothalamic and pituitary hormones Thyroid hormones and anti thyroid drugs Parathormone, calcitonin and vitamine D. Insulin. Glucagon Oral hypoglycaemic agents ACTH and Corticosteroids Androgens and Anabolic Steroids Estrogens and Oral contraceptives Progesterone Drugs acting on uterus. General principles of Chemotherapy Sulfonamides and cotrimoxazole Antibiotics: Penicillins Cephalosporins Erythromycin Quinolones Miscellaneous antibiotics. Chemotherapy of tuberculosis Leprosy Chemotherapy of Fungal diseases Chemotherapy of viral diseases Urinary tract infections sexually transmitted diseases Chemotherapy of malignancy Immunosuppressive agents Principles of toxicology Definition of poision,General principles of treatment of poisioning Treartment of Barbiturates, opioids, Organophosphorous and atropine poisioning Heavy metals and heavy metal antagonists Score Modes of Assessment Assignment/Attendance 10 Presentation/Tests 10 Mid semester exam-I 40 Mid semester exam-II 40
  • 5. Modes of Assessment: Instruction for students: 1. Assignment marks will be awarded only after conducting viva-voce which will be on the day of assignment submission. 2. Late submission is not permissible and will attract minimum awards. 3. For presentation, whole of the class is divided in to 5 groups and each group is again subdivided into 3 subgroups. Each subgroup has 4 students. 4. Each group is assigned different subject for the presentation day. 5. The presentation day attendance is equivalent to 4 lectures. 6. The synopsis must be submitted one week before the presentation. 7. 75% attendance is mandatory, below this percentage; student will not be allowed to appear in the examination. 8. The students will record the details of practicals in the practical note book and get it checked every time from the instructor after the experiment has been completed Text books: 1. Tripathi, Experimental Pharmacology, Edition 5. 2. Kulkarni, S.K., A Handbook of Experimental Pharmacology. References: 1. Goodman and Gilman’s, The Pharmacological Basis of Therapeutics. Editor J.G. Hardman et al. Pergamon Press. 2. Rang, M.P., Dale M.M. and Riter, J.M. Pharmacology. Churchill Livi.